A New Triterpene Glycoside from the Sea Cucumber Holothuria Scabra Collected in Vietnam

Abstract

Bioassay guided fractionation led to the isolation of a new triterpene glycoside, holothurinogenin B (1) along with three known compounds, holothurin B (2), holothurin A (3), and holothurin A₂ (4), from the methanol extract of the Vietnamese sea cucumber Holothuria scabra. Their structures were deduced from the spectral analysis (1D-NMR, 2D-NMR, MS) and chemical evidences. Keywords: Triterpene glycosides, Sea cucumber, Holothuria scabra, Holothurinogenin B. AJSTD Vol. 23 Issue 4 pp. 253-260 (2006)