SODIUM SULFIDE-PROMOTED REACTION OF 2-AMINOBENZAMIDE AND BENZYL ALCOHOLS WITH ELEMENTAL SULFUR: A NOVEL APPROACH WITH 2-ARYL-QUINAZOLIN-4(3H)

DOI: 10.18173/2354-1059.2022-0044

Authors

  • Doan Thi Yen Oanh1,2
  • Vo Ngoc Binh2
  • Ngo Quoc Anh2

Keywords:

Abstract

A simple metal- and solvent-free method for the synthesis of 2-aryl- 4(3H)-quinazolinone derivatives from 2-aminobenzamide and benzyl alcohols in the presence of S8\DMSO as an oxidizing agent and promoted by Na2S.5H2O has been reported. Five 2-aryl-4(3H)-quinazolinone derivatives were synthesized with yields from 23% to 86%. 

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Published

2023-09-19

Issue

Vol. 3 No. 67 (2022): Tháng 10 năm 2022

Section

ARTICLES