PHÂN TÍCH ĐẶC ĐIỂM CẤU TRÚC CỦA SULFATE POLYSACCHARIDE TÁCH CHIẾT TỪ LOÀI RONG SARGASSUM SERRATUM

Tóm tắt

Fucoidan was isolated from Vietnamese brown seaweed Sargassum serratum and its structural
characteristics were analyzed. Through chemical analysis, IR, and NMR spectroscopy, the structural
features of S. serratum fucoidan were determined. The study identified S. serratum fucoidan as belonging to
the galactofucan sulfate group. The primary constituents are α-L-fucose, β-D-galactose, xylose, mannose,
rhamnose, and glucose, with a molar ratio of 1 : 0.12 : 0.045 : 0.003 : 0.002. The main substituent is sulfate,
with a very small amount of acetyl groups. Sulfate groups are located at C4 and C2 positions in the fucosyl
and galactosyl residues. The glycosidic bonds in the main chain of fucoidan are predominantly (1→3)
linkages, with branch chain (1→2) linkages.