DETERMINATION OF SALBUTAMOL AND RACTOPAMINE BY CAPILLARY ELECTROPHORESIS WITH CONTACTLESS CONDUCTIVITY DETECTION (CE-C4D)

Abstract

    The illegal use of of β-agonist in cattle feed to enhance muscle growth and reduces fatin affected animal has raised a big concern to consumers in Vietnam in recent timesince their residues in meat can induce serious diseases such as muscle cramps,disturbed vision and eye pain, irregular heartbeat,.. In this article, a simple method forthe simultaneous determination of 2 common β-agonist: Salbutamol and Ractopamineby capillary electrophoresis using contactless conductivity detector was developed. Thelimits of detections were 0.5 and 0.7 μg/mL for Salbutamol và Ractopamine,respectively. This method provides average recoveries for salbutamol and ractopamineof 95,8% - 101,3%. The optimized procedure was applied to determine the Salbutamoland Ractopamine in several pig feed and pig meat samples with high confidence.