NGHIÊN CỨU ỨNG DỤNG CẢM BIẾN SINH HỌC ĐIỆN HÓA TRÊN CƠ SỞ VI ĐIỆN CỰC BIẾN TÍNH XÁC ĐỊNH DƯ LƯỢNG THUỐC BẢO VỆ THỰC VẬT

Tóm tắt

In this study, electrochemical biosensors based on conductive polymer (polyaniline, PANi) and carbon
nanomaterials (graphene, Gr) were fabricated on a screen-printed electrode (Pt-SPE) to detect plant
protective drugs (Methamidophos). PANi films were synthesized onto microelectrodes using cyclic
voltammetry (CV) then coated Gr film directly onto the electrode. The PANi/Gr bilayer hybrid material
has good electrical conductivity, high porosity, good adhesion to biological molecules, and fast
electronic transmission. PANi/Gr hybrid membranes were used to fabricate disposable
acetylcholinesterase sensors to detect acetylthiocholine (ATCh). The electrochemical sensor is capable
of detecting the Methamidophos with a detection limit of 1-50 ppm for a period of 10 minutes with the
error permitted limit (15%). The electrochemical sensor provides a very promising technical solution to
monitor topical acetylthiocholine levels in patients with neurological diseases and to identify
neurotoxins such as sarin and pesticides.