THE CLINICAL CHARACTERISTICS AND IN-HOSPITAL OUTCOMES OF PATIENTS AGED ≥70 UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION FOR ST-ELEVATION MYOCARDIAL INFARCTION

Abstract

Background: ST elevation myocardial infarction (STEMI) is one of the leading causes of mortality and morbidity among cardiovascular diseases. The data on patients aged ≥70 with STEMI performing primary percutaneous coronary intervention (PPCI) is limited.

Objectives: To evaluate the clinical characteristics and in-hospital outcomes of patients aged ≥70 who presented with STEMI and underwent PPCI.

Method: This was a prospective single-center case series. The patients diagnosed with STEMI who performed PPCI were included.

Results: Between January and September 2018, a total of 288 consecutive all-comers with STEMI and underwent PPCI were included. Of 288 admitted patients, 48 (16.6%) patients were ≥70 years old. There was an identical severity of coronary artery disease between the two groups. Compared with younger patients, individuals aged ≥70 were less likely to be treated with beta-blockers (77.1% vs. 88.8%, P=0.001) or ACEIs/ ARBs (89.6% vs. 98.3%, P=0.001); and at increased risk of bleeding (10.4% vs. 2.1%, P=0.004), cardiogenic shock (12.5% vs. 4.6%, P=0.032), and ventricular tachycardia/ fibrillation (6.3% vs. 1.3%, P=0.027). In-hospital mortality was not significantly different between the two groups.

Conclusion: Individuals aged ≥70 following PPCI for STEMI were more likely to have in-hospital bleeding events, cardiogenic shock, and ventricular tachycardia/ fibrillation.

Keywords: ST elevation myocardial infarction (STEMI), primary percutaneous coronary intervention (PPCI), elderly