Đánh giá tiềm năng ức chế sinh trưởng tế bào ung thư gan của dịch chiết từ nhựa vàng của cây Nha đam

Tóm tắt

    Liver cancer is one of the most common fatal types of cancer over the world. Conventional cancer treatments such as surgery, chemotherapy and radiation therapy are costly and requires long-term commitment to be effective, which eventually leads to financial burden and suffering of patients and their families. Natural extracts originated from plants have been studied and exploited as pharmaceutical products or functional products supporting cancer treatments for years. The purpose of this study is to evaluate the antineoplastic activity of Aloe vera on Huh-7 cell line. The results showed that  dimethyl sulfoxide extract from Aloe vera latex had cytotoxicity on Huh-7 cell line after (24-48) h of treatment with IC₅₀ value at (160.72 ± 2.95) µg/mL and (156.41 ± 1.30) µg/mL respectively. Besides, the extract also inhibited the migration of cancer cells in (24-48) h treatment at minimum concentration of 100 µg/mL. Hence, Aloe vera latex extract is considered a potential anticancer agent against the proliferation of hepatic cancer cell.