Chemical constituents from chloroform extract of Chromolaena odorata l., asteraceae leaves

Abstract

3kg leaves of Chromolaena odorata L. collected in District 2, HCM city was extracted and separated to yield CHCl₃ extract (90,22g). CHCl₃ extract was further separated via flash column to obtain 7 fractions.  Quercetin 7,4’ – dimethylether (Ombuin) (C₁; 144,2mg) and 7 – dihydroxy 3’,4’ – dimethoxyflavon (C₃; 129,3mg) were isolated from these fractions through fractional crystallization. The structures of isolated compounds were determined on the basis of spectroscopic analyses (MS and NMR). Additionally, the structure of C₂ (40,0mg) is being elucidated. Further studies on constituents from another fractions of this plant are in process.