HOẠT TÍNH KHÁNG VIÊM VÀ CHỐNG OXY HÓA IN VITRO CỦA CAO CHIẾT TỪ LÁ CÂY DẺ TRÙNG KHÁNH (CASTANEA MOLLISSIMA) Ở VIỆT NAM

Abstract

The anti-inflammatory and antioxidant activity of the crude extract (TK); fractional extracts including: n-hexane extract (TKH), ethyl acetate extract (TKE)
and methanol extract (TKM) of Castanea mollissima collected in Trung Khanh district, Cao Bang province has been investigated using DPPH assay. The results
showed that the crude extract (TK) exhibited good in vitro anti-inflammatory and antioxidant activities with SC50 value of 26.12µg/mL and IC50 value of
20.2µg/mL, respectively. As for fractional extracts, ethyl acetate extract (TKE) exhibited the best in vitro anti-inflammatory and antioxidant activities with SC50
value of 20.65µg/mL and IC50 value of 18.5µg/mL, respectively while the remaining fractions showed moderate and weak activity.