Cấu trúc và hoạt tính ức chế enzyme α-glucosidase của hai hợp chất steroid được phân lập từ thân cây quéo mangifera reba.

Abstract

Study on the ethyl acetate extract from the stem of Mangifera reba have isolated β-daucosterol (1) and 6¢-O-acetyl-β-daucosterol (2). The chemical structures of these compounds were elucidated based on the NMR spectroscopic analysis and comparison with the literatures. These compounds showed more potent inhibitory activity, with IC₅₀ values 207.3 and 83.5 μM respectively, than that of a positive control acarbose (IC₅₀, 214.5 μM)