SURVEY OF ULTRA-SENSITIVE TROPONIN I CONCENTRATION AND ITS RELATIONSHIP WITH LIPID PROFILES IN PATIENTS WITH TYPE 2 DIABETES GENERAL INFORMATION

Abstract

Cardiovascular disease (CVD) is the leading cause of premature death in patients with type 2 diabetes mellitus (T2D), with dyslipidemia playing a significant role. High-sensitivity Troponin I (Hs-TnI) is a cardiovascular biomarker with high diagnostic value and is considered the gold standard for the early detection of myocardial injury and clinical cardiovascular risk.
In Vietnam, there have been no studies evaluating the association between Hs-TnI levels and lipid profiles in patients with T2D. Therefore, this study was conducted to investigate Hs-TnI levels and examine their relationship with lipid profiles in T2D patients, thereby providing valuable clinical data for early detection of cardiovascular risks in these patients.
Objectives: Evaluate high-sensitivity Troponin I concentration in patients with and without type 2 diabetes, analyze the relationship between Hs-TnI with lipid profile indices.
Results: The median Hs-TnI level in the type 2 diabetic patient group was 6 pg/mL [2-16], significantly higher compared to 1 pg/mL [1-3] in the non-diabetic group (p < 0.001). However, this study found no significant correlation between Hs-TnI levels and lipid profile indices in either group (p > 0.05).
Conclusion: Hs-TnI levels differed significantly between diabetic and non-diabetic groups. Nevertheless, no association between Hs-TnI levels and lipid profiles was observed in this study.