Studying conditions, physiologycal and biochemical characteristics, and the effectiveness of treatment support for leukopenia in cats caused by feline panleukopenia virus at the Veterinary hospital of Dong Thap Community College

Abstract

The feline panleukopenia virus (FPV)-induced leukopenia was studied at the Veterinary Clinic, Dong Thap Community College, from December 2022 to December 2023. This study investigated the prevalence of the disease, monitor physiological and biochemical blood parameters, and evaluate the effectiveness of supportive treatment for FPV-infected cats. Both clinical and paraclinical assessments were applied. Cats exhibiting symptoms were sampled for FPV diagnosis using a test kit, and random blood samples (n=10) were taken for physiological and biochemical analysis, along with supportive treatment. Of the 273 cats, 36 (13.19%) tested positive for FPV, with the highest infection rate observed in cats aged 1-6 months (45.83%) and the lowest in cats over 12 months (15.78%). Domestic breed cats had a higher infection rate than foreign breeds (P<0.05), while the infection rate between male and female cats showed no significant difference (P>0.05). Notably, the infection rate among vaccinated cats was 7.94%, significantly lower than that of unvaccinated cats (67.39%, P<0.01). Blood tests revealed a marked decrease in leukocytes (1.36 x 10³/mm³) and platelets (163 x 10³/µl), while red blood cell levels remained normal. Treatment outcomes indicated that 33.34% of cats recovered within 5-7 days, while 11.10% showed symptomatic improvement, and 55.56% did not recover.