MOLECULAR IODINE FOR THE SYNTHESIS OF 2-ARYLQUINOXALINES

Tóm tắt

This study gave a new method to synthesize 2-arylquinoxalines from o-phenylenediamines and aryl methyl ketones. The reaction occurred via molecular iodine[1]promoted direct C(sp3 )-H bond functionalization of aryl methyl ketones under transition metal-free conditions. The utilities of this study are the (1) direct Csp3 -H bond functionalization, (2) inexpensive and abundant iodine source, (3) transition metal-catalyst free, and (4) different synthesis of 2-arylquinoxalines from common materials.