Molecular epidemiological characteristics of E. coli strains carrying the mcr-1 gene isolated from healthy human feces, domestic animal feces, food and water in Thanh Ha commune, Thanh Liem district, Ha Nam province

Abstract

Colistin is a critically important antimicrobial for the treatment of carbapenem-resistant gram-negative intestinal infections. E. coli strains carrying the colistinresistant mediated colistin resistance (mcr-1) gene have been globally distributed, found in humans, animals and the environment with diverse resistance mechanisms, namely intrinsic, mutation, and horizontal gene transfer [1]...