Evaluate the safety and effectiveness of Bacillus probiotic spores in children with persistent diarrhea

Authors

  • Thuy Ha Dang*, Minh Dien Tran, Thi Bich Thuy Phung, Thi Viet Ha Nguyen, Hai Yen Vu, Thi Minh Luong, Thi Thu Trang Nguyen, Thi Thanh Nga Pham, Thi Ngoc Hong Nguyen, Thi Huong Le, Van Ngoan Nguyen, Minh Hang Nguyen, Thi Huong Trinh
  • Thi Phuong Anh Bui, Thi Huyen Bui, Thi Ngoc Hao Vo, Thi Van Anh Nguyen, Hoa Anh Nguyen

Keywords:

Bacillus, persistent diarrhea, probiotic, spore

Abstract

Persistent diarrhea in children under 24 months old has been a global public health concern, including in Vietnam. Therefore, the authors conducted a randomised, double-blind, placebocontrolled clinical trial to evaluate the effectiveness of two Bacillus spore probiotic suspensions, namely LiveSpo CLAUSY
containing B. clausii at 2 billion CFU/5 ml ampoule; and LiveSpo DIA30 containing B. subtilis, B. clausii, and B. coagulans at 5 billion CFU/5 ml ampoule, as a supportive treatment for children with persistent diarrhea...

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Author Biographies

  • Thuy Ha Dang*, Minh Dien Tran, Thi Bich Thuy Phung, Thi Viet Ha Nguyen, Hai Yen Vu, Thi Minh Luong, Thi Thu Trang Nguyen, Thi Thanh Nga Pham, Thi Ngoc Hong Nguyen, Thi Huong Le, Van Ngoan Nguyen, Minh Hang Nguyen, Thi Huong Trinh

    Vietnam National Children's Hospital, 8/879 La Thanh Street, Lang Thuong Ward, Dong Da District, Hanoi, Vietnam

  • Thi Phuong Anh Bui, Thi Huyen Bui, Thi Ngoc Hao Vo, Thi Van Anh Nguyen, Hoa Anh Nguyen

    LiveSpo Pharma Company Limited, N03 T5 Ngoai Giao Doan, Xuan Tao Ward, Bac Tu Liem District, Hanoi, Vietnam

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Published

2024-06-25

Issue

Vol. 66 No. 6B (2024): TẬP 66, SỐ 6, THÁNG 6 NĂM 2024

Section

KHOA HỌC KỸ THUẬT VÀ CÔNG NGHỆ