Development and validation of quantitative procedure of clotrimazole and eugenol in gel product using high-performance liquid chromatography

Authors

  • Mong To Tam Tran, Thi Thanh Vy Dinh, Hoai Hieu Vo, Thi Hoang Yen Pham, Thi Loan Le
  • Dinh Nga Nguyen

Keywords:

Abstract

Vulvovaginitis is a prevalent gynaecological ailment worldwide, often attributed to bacteria, Candida fungi, or Trichomonas. The synergistic action of antifungal agents and essential oils can enhance the efficacy against pathogenic microorganisms. In this study, a simultaneous quantitative method for determining clotrimazole and eugenol in a laboratory-compounded gel product was developed using high-performance liquid chromatography
with a photodiode array detector (HPLC-PDA)...

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Author Biographies

  • Mong To Tam Tran, Thi Thanh Vy Dinh, Hoai Hieu Vo, Thi Hoang Yen Pham, Thi Loan Le

    Yersin University, 27 Ton That Tung Street, Ward 8, Da Lat City, Lam Dong Province, Vietnam

  • Dinh Nga Nguyen

    University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Street, Ward 11, District 5, Ho Chi Minh City, Vietnam

Published

2024-06-14

Issue

No. 2C (2024): JUNE 2024 . VOLUME 66 NUMBER 2

Section

PHYSICAL SCIENCES