Synthesis of acetamides bearing 3-aryl-3,4-dihydroquinazolin-4-one and 2-thioxothiazolidin-4-one moieties as novel derivatives

Tóm tắt

Five new derivatives of N-(4-oxo-2-thioxothiazolidin-3-yl)-2-((3-aryl-4-oxo-3,4-dihydroquinazolin-2-yl)thio) acetamides have been synthesized successfully through a four-step process from anthranilic acid and aryl isothiocyanates as starting materials. The total yields ranged from 29 to 31% and these structures were determined by IR, 1H-NMR, 13C-NMR, and HR-MS spectra.