In silico screening of alkaloids as potential inhibitors of epidermal growth factor receptor

Các tác giả

  • Bui Thanh Tung*, Nguyen Nhu Son, Nguyen Bao Kim, Nguyen Hai Ha 
  • Pham Thi Kim Dung
  • Nguyen Thanh Tra

Từ khóa:

Tóm tắt

The epidermal growth factor receptor (EGFR) belongs to the HER/erbB receptor tyrosine kinase (RTK) family, serving as a crucial target for cancer treatment. Anti-EGFR drugs, used as a primary treatment for patients with advanced EGFR gene mutations such as T790M, C797S, and L858R, have shown greater efficacy and safety compared to standard chemotherapy...

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Tiểu sử tác giả

  • Bui Thanh Tung*, Nguyen Nhu Son, Nguyen Bao Kim, Nguyen Hai Ha 

    University of Medicine and Pharmacy, Vietnam National University-Hanoi, 144 Xuan Thuy Street, Dich Vong Hau Ward, Cau Giay District, Hanoi, Vietnam

  • Pham Thi Kim Dung

    Hanoi Obstetrics and Gynecology Hospital, 929 La Thanh Street, Ngoc Khanh Ward, Ba Dinh District, Hanoi, Vietnam

  • Nguyen Thanh Tra

    Research and Development Department, Phap Viet Xnk and Investment Joint Stock Company (PHAVIMEX), Lane 63, Phu Do Ward, Nam Tu Liem District, Hanoi, Vietnam

Đã Xuất bản

2023-09-14

Số

Số 3C (2023): SEPTEMBER 2023 . VOLUME 65 NUMBER 3

Chuyên mục

LIFE SCIENCES