MECHANISM AND EFFECTS OF SALMONELLA ON HUMAN HEALTH

Abstract

Salmonella is a type of intestinal bacteria, one of the causes of food poisoning in humans. Salmonella infection remains a major public health concern worldwide, contributing to the economic burden through costs associated with disease surveillance, prevention and treatment. In this paper, we present an overview of studies on infectious sources, pathogenic mechanisms, epidemiology, effects of Salmonella on human health and preventive measures. The emergence of multidrug-resistant Salmonella (MDRS) is having a major impact on the effectiveness of antibiotic treatment and the increasing incidence of MDRS strains, which can lead to increased mortality from Salmonella infections. Epidemiological studies have shown that serotypes of multidrug-resistant Salmonella are more virulent than susceptible strains, as demonstrated by increased severity and longer duration of illness. Precautionary measures have been suggested to eliminate the spread of Salmonella infections. While maintaining effective food hygiene and water sanitation remains fundamental, additional measures such as limiting the indiscriminate use of antibiotics in animal husbandry are important.