A CASE REPORT OF INTRAHEPATIC CHOLANGIOCARCINOMA TREATED WITH GEMCITABINE/CIPLATIN AT ONCOLOGY CENTER OF THAI NGUYEN CENTRAL HOSPITAL

Abstract

In general, intrahepatic cholangiocarcinoma (IHCC) accounts for 5-20% of all primary liver cancer cases. However, in Viet nam,  the  exact incidence of IHCC is not known because it is not easy to be diagnosed and often is in combine with other type of  liver cancer. At Oncology Center of Thai nguyen Center Hospital, there are a few cases of IHCC diagnosed. With the aim of providing information for diagnosis and treatment, we report a case of 36 year-old man with IHCC in our Center. Abdominal CT scanner examination revealed the large tumour of the left liver lobe. Histopathology of the tumour was cholangiocarcinoma. The patient was diagnosed T3N0M0 IHCC and was treated with Gemcitabine/Cisplatin regiment for 8 cycles. Partial response was achieved with the good tolerance (leucopenia grade 1, neutropenia grade 1, anemia grade 1, vomiting grade 1, and there were no renal and liver toxicities). Preliminarily, IHCC is fairly sensitive with chemotherapy and Gemcitabine/Cisplatin regiment is probably suitable in the field of response and tolerance for the IHCC patients.