TỔNG HỢP MỘT SỐ XETON alpha,beta- KHÔNG NO ĐI TỪ 6-AXETYL-5-HIĐROXI-4-METYLCUMARIN

Abstract

6-acetyl-5-hidroxy-4-methylcoumarin was prepared by cyclic reaction of 2,4-dihidroxyacetophenon with ethyl acetoacetate. The product was then transformed by condensation with aromatic aldehydes to form a series of new α,β-unsaturated ketones (7 compounds). Structure of these products was confirmed by IR, ¹H NMR, ¹³C NMR, HSQC, HMBC spectroscopic data. Biological activities of these compounds have been inves.