SOME FACTORS RELATED TO HYPERGLYCEMIA IN CANCER PATIENTS IN THAI NGUYEN NATIONAL HOSPITAL

Abstract

This study aims to analyze some factor related to hyperglycemia in cancer  patients in Thai Nguyen National Hospital. By a longitudinal study method of 266 cancer patients were treated at least 3 cycles of chemotherapy. The results show that prechemotherapy, after the 3^rd cycle, the mean concentration of plasma glucose levels respectively were 4.97±0.45 mmol/L, 5.33±0.99 mmol/L, 5.44±1.12 mmol/L, with statistically significant differences. After the 3rd cycle,  the prevalence of hyperglycemia in patients with colon cancer, in patients treated with 5FU, in patients treated with FOLFOX regimen were higher than  in patients with breast cancer, in patients treated with cyclophosphamid, in patients treated with AC regimen, with respectively statistically significant differences (OR: 2.31; 95% CI: 1.39-3.87; p<0.01); (OR: 2.15; 95% CI: 1.28-3.61; p<0.01); (OR: 2.06; 95% CI: 1.21-3.48; p<0.01). Increased plasma glucose levels after chemotherapy. Plasma glucose levels changed differently by tumor types chemotherapeutic agents and regimens. After the 3^rd cycle, the prediabetes, diabetes were 19.9% and 3.4%.